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Who can join the blood stem cell and marrow registry as a potential donor?

Jan 27, 2022 by Gift of Life News

Many potential donors ask us on our social media accounts or at registration events if they are able to donate, or even if they can join the registry. 

Who can join the registry? Anyone 18 to 35 years old who is in general good health can complete a swab kit and the health questionnaire and join the registry at no cost. The processing of these swab kits is paid for by our financial contributors. 

Prospective donors 36 to 60 years old are asked to contribute $60 for the cost of processing their swab kit, as they are much less likely to be called as a match. 

Close to 90% of donors requested by transplant centers are 18 to 35, due to the higher rate of success for the patients. Studies of transplant results clearly show that hematopoietic stem cells and bone marrow collected from younger donors produce a significantly better outcome for patients.  Click here to read our article on this topic.

The health questionnaire you will complete during registration screens for conditions that could be harmful to the donor while donating, or could be harmful to the patient receiving the transplant. 

Our primary concern as a donor registry is the health and safety of our donors, so every person who is asked to donate peripheral blood stem cells or bone marrow is given a thorough medical exam to ensure their health will not be compromised by the collection process.

If your medical history includes one of the restricted health conditions that increases your risk during the collection process, Gift of Life may not be able to register you. To learn if a particular condition disqualifies you from joining the registry, click here to view the Conditions List.   If you are unsure whether a restriction applies to you, completing the health questionnaire as part of the registration process will help determine your ability to join the registry.

Some common questions about registering and donating are answered below. We are always available to answer your questions and there is plenty of information about donating throughout our website. Start here to learn about the blood stem cell and bone marrow donation process and click here to read real stories about our donors’ experiences, including many who have met their recipients.

1. Is a certain blood type needed to be a donor?

Blood type is not a factor in this type of transplant and people with any blood type can donate. When peripheral blood stem cells or bone marrow are transplanted to a patient, the patient will develop the blood type of their donor as their new bone marrow begins producing blood cells. Therefore, blood type is not a requirement of becoming a donor.

2. Can I donate if I have tattoos or piercings?

Yes, you can join the registry and if you are a match for a patient, can donate peripheral blood stem cells or bone marrow. Today’s tattoo artists follow safety precautions to prevent the transmission of blood-borne diseases like hepatitis and HIV, and every donor receives a thorough medical examination before donating. 

3. Can I join Gift of Life’s registry and donate if I identify as LGBTQ+?

Yes! Gift of Life Marrow Registry welcomes you. If you are a match for a patient, you will receive the same medical examination and tests as all other potential donors, and may have the opportunity to save someone’s life. People have often heard that gay men are not allowed to join the registry due to regulations that apply to blood banks. This is false – gay men can join the registry. 

4. Can I donate if I have a bad back, a neck injury, or a problem with my hips?

Some types of back, neck and hip injuries or a chronic condition such as osteoporosis, for example, may prevent you from donating. We urge everyone to complete the health questionnaire accurately during registration, so eligibility to donate can be determined. Every volunteer must be able to donate either peripheral blood stem cells or bone marrow in a safe and comfortable manner. Because bone marrow is collected from the iliac crest of the pelvis while the donor is face down, it is important that every donor have no issues with the back, hip or neck. Gift of Life’s concern is for the donor first, and safety is our highest priority.

5. Can I donate if I have lived in England for a period of time?

Due to the emergence of Bovine Spongiform Encephalopathy (aka Prion Disease or Mad Cow Disease) in the United Kingdom in the 1980s, Americans who spent more than three months in England were previously restricted from donating blood. (The restriction was lifted during the COVID-19 pandemic and is not expected to be reinstated.) However, blood donation regulations do not apply to donors of blood stem cells or bone marrow. Potential donors who have spent three or more months in England are welcome to join the registry.

6. Can I donate if I have had malaria, typhus, zika, ebola, chikungunya, or another tropical disease? 

Some tropical diseases or parasitic infections may prevent you from donating. When you join the registry, the first step is a health questionnaire. Some chronic health conditions disqualify individuals from joining the registry, as they pose a hazard either to the donor or to the recipient. If you are unsure complete the health questionnaire to determine your ability to donate. 

7. Can I donate blood stem cells or bone marrow if I have previously been diagnosed with a form of cancer or am a transplant recipient myself?

Transplant recipients may not donate blood stem cells or bone marrow, due to the risk it represents to their own health. Many individuals who were diagnosed with cancer at some point in their lives may be disqualified from donating, depending on the type and location of the cancer. For example, a small spot of benign skin cancer that was thoroughly removed may not prevent you from donating. For every donor, final approval to donate is based on a thorough medical examination.

8. What other conditions might prevent me from joining the registry or donating peripheral blood stem cells or bone marrow? 

Find a list of the most common medical conditions that prevent someone from donating by clicking here.

Note that this list may change at times due to the emergence of new medical research and information, and updates to federal regulations and guidelines.