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Fact and Fiction: The Truth About Donating Bone Marrow and Stem Cells

Apr 26, 2019 by Gift of Life News

Above: Logan donated peripheral blood stem cells to save the life of a man battling leukemia.

Let’s face it: when it comes to donating bone marrow, people have a lot of misconceptions. Let’s look at some of these and set the record straight. Lives depend on it, because a stem cell or bone marrow transplant can cure 100 diseases, including blood cancers like leukemia and lymphoma, sickle cell disease, inherited immune disorders, and many more. 

Top 5 Misconceptions


Myth 1. Once you sign up, you have to donate

The truth is that donating bone marrow or stem cells is purely voluntary. If you are between 18 and 35 and in good health, you can join the registry, but the chances of being called are fairly low. That doesn’t mean it’s not important to register – you could get the opportunity to save someone’s life, which is rather incredible. You can expect to change someone else’s life, but what most donors don’t expect is how meaningful donating is to them. Saving another person is big stuff. 


Myth 2. Only a family member can donate to a patient in need 

Most people believe that only a patient’s family members can donate to them, but the opposite is true. Only about 30 percent of patients find a donor within the family. The other 70 percent must seek an unrelated donor in the worldwide registry. If no donor is found, they often run drives to recruit new donors in the hope of finding a match. The best chance of a match is with someone from the same genetic heritage, so it’s incredibly important that more people of diverse background and mixed race join the registry.  Click here to learn more about the need to diversify the registry.


Myth 3. Donating bone marrow or stem cells is dangerous

One of the biggest myths about marrow donation is that it’s painful and dangerous, requiring an invasive surgery. The truth is that there are two methods of donating, and both are outpatient procedures with no long-term side effects.

The most frequently used method, more than 90% of the time, is peripheral blood stem cell donation. The donor spends four to six hours in a comfortable chair or bed, while blood is drawn from one arm, the needed stem cells are separated out and the remaining blood is returned to the other arm. Donors can watch movies or chat with friends during the process, and go home when it is finished. 

The 10% who donate bone marrow, most often requested for children, can expect a one-and-a-half to two-hour procedure. While under general anesthesia, a doctor will collect liquid marrow from the iliac crest of the hip bone using a syringe. Donors go home after the anesthesia wears off, and may feel a backache for several days, treatable with Tylenol or similar medications. There is no long-term recovery and donors resume a normal routine in one to three days. Your bone marrow and stem cells grow back on their own, and your recipient gains a second chance at life.


Myth 4: My personal information could be shared

With the huge popularity of genealogical DNA testing, many people wonder if Gift of Life shares any information with other organizations. Your information is protected by the same regulations that your own doctor complies with. We test for specific factors that show whether you could be a perfect immune system match for a patient, and this data is confidential. Your name does not appear in the worldwide marrow registry; only Gift of Life knows your identity.


Myth 5: You're going to clone me! 

Well, there’s one more myth that a lot of people ask us about at the swabbing table when they join the registry: Are you going to clone me? Most of them are joking, but we are asked so often that we’d like to address it. First of all, human cloning has never been done, and due to the way the nucleus of human cells is structured, will likely remain impossible for many years to come. Even if scientists someday discover a process, creating just one clone would cost many millions of dollars. We hate to disappoint everyone, but cloning you just isn’t in our budget! 

The bottom line is that joining the registry is a great opportunity to save someone else’s life – and you may even get the chance to meet them someday! It’s a big responsibility, but every donor tells us it’s an incredible and rewarding experience, and they would be thrilled to do it again.

Do you have questions about stem cell or bone marrow donation we can answer? Email us,


Transplants can cure 100 diseases including blood cancers, sickle cell disease, and inherited immune disorders

Rebbe Eli donated peripheral blood stem cells in about five hours. Hannibal donated twice to save a teenage girl's life: first bone marrow and then stem cells. Our hero! Kelly gave peripheral blood stem cells in just a few hours to give her recipient a second chance at life.


(L) Rebbe Eli donated stem cells to a 62-year-old woman fighting a bone marrow cancer, giving her a second chance at life.

(C) Hannibal donated twice to a teenage girl battling leukemia. He first donated bone marrow, then gave a second donation of stem cells to aid in her recovery. 

(R) Kelly relaxes comfortably as she donates stem cells. Most donors spend their time watching movies and chatting with a family member or friend who accompanied them. 


To learn more about donating, visit the Donor Resources section of our site by clicking here